Mitochondrial carrier family (SLC25)

GPTKB entity

Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:solute_carrier_family
gptkbp:alternativeName gptkb:SLC25_family
mitochondrial solute carrier family
gptkbp:associatedWith mitochondrial diseases
gptkbp:contains gptkb:aspartate/glutamate_carrier
ADP/ATP translocase
phosphate carrier
carnitine/acylcarnitine translocase
citrate carrier
oxoglutarate carrier
gptkbp:evolutionaryConservation highly conserved in eukaryotes
gptkbp:foundIn mitochondrial inner membrane
gptkbp:function transport of metabolites across mitochondrial inner membrane
gptkbp:geneSymbolPrefix SLC25A
https://www.w3.org/2000/01/rdf-schema#label Mitochondrial carrier family (SLC25)
gptkbp:InterPro IPR018108
gptkbp:memberOf solute carrier superfamily
gptkbp:numberOfMembers over 50 in humans
gptkbp:OMIM 601506
gptkbp:proteinFamily PF00153
SLC25
gptkbp:structure six transmembrane alpha helices
gptkbp:transportedMolecules amino acids
nucleotides
metabolites
cofactors
inorganic ions
gptkbp:UniProtID P02722
gptkbp:bfsParent gptkb:P9WQK1
gptkbp:bfsLayer 8