Statements (46)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:protein
gptkb:S_protein |
| gptkbp:binds |
gptkb:ACE2
|
| gptkbp:component |
gptkb:SARS-CoV-2_virion
|
| gptkbp:disulfideBond |
present
|
| gptkbp:domain |
receptor binding domain
S1 domain S2 domain |
| gptkbp:function |
mediates viral entry into host cell
|
| gptkbp:gene |
SARS-CoV-2 spike glycoprotein gene
|
| gptkbp:glycosylation |
present
|
| gptkbp:GOProcess |
viral entry into host cell
|
| gptkbp:hasCleavageSite |
S1/S2 site
S2' site |
| gptkbp:hasComponent |
viral envelope
|
| gptkbp:hasCytoplasmicTail |
present
|
| gptkbp:hasGOFunction |
receptor binding
|
| gptkbp:hasPfamDomain |
PF01601
PF09408 |
| gptkbp:hasUniProtEntryName |
SPIKE_SARS2
|
| https://www.w3.org/2000/01/rdf-schema#label |
P0DTC2
|
| gptkbp:InterPro |
IPR002552
IPR027400 |
| gptkbp:involvedIn |
membrane fusion
viral entry |
| gptkbp:length |
1273 amino acids
|
| gptkbp:molecularWeight |
141 kDa
|
| gptkbp:numberInSeries |
MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGSCCKFDEDDSEPVLKGVKLHYT
|
| gptkbp:organism |
gptkb:Severe_acute_respiratory_syndrome_coronavirus_2
|
| gptkbp:PDB |
7A94
6VSB 6XR8 7BNM |
| gptkbp:postTranslationalModification |
glycosylation
cleavage by furin |
| gptkbp:reviewedBy |
gptkb:UniProtKB/Swiss-Prot
|
| gptkbp:signalPeptide |
present
|
| gptkbp:structure |
trimer
|
| gptkbp:subcellularLocation |
viral envelope
|
| gptkbp:target |
gptkb:COVID-19_vaccines
neutralizing antibodies |
| gptkbp:transmembraneDomains |
present
|
| gptkbp:UniProtID |
gptkb:P0DTC2
|
| gptkbp:bfsParent |
gptkb:3LU6
|
| gptkbp:bfsLayer |
8
|