|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
Growth hormone
|
|
gptkbp:associatedWith
|
gptkb:Laron_syndrome
Isolated growth hormone deficiency
|
|
gptkbp:biologicalProcess
|
growth hormone activity
positive regulation of cell growth
|
|
gptkbp:cellularComponent
|
extracellular region
|
|
gptkbp:chain
|
28-217
|
|
gptkbp:EC_number
|
3.6.1.-
|
|
gptkbp:Entrez_Gene_ID
|
ENSP00000354587
ENSG00000197416
|
|
gptkbp:expressedIn
|
Pituitary gland
|
|
gptkbp:function
|
Stimulates growth, cell reproduction, and regeneration
|
|
gptkbp:gene
|
gptkb:GH1
|
|
gptkbp:HGNC_ID
|
HGNC:4261
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P01270
|
|
gptkbp:InterPro
|
IPR001400
|
|
gptkbp:KEGGID
|
hsa:2688
|
|
gptkbp:length
|
217
|
|
gptkbp:locatedOnChromosome
|
gptkb:GH1
17
|
|
gptkbp:location
|
gptkb:17q23.3
|
|
gptkbp:molecularWeight
|
22129
|
|
gptkbp:OMIM
|
139250
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
1AXI
1HGU
1HKA
1HWG
1HWA
1HWB
1HWC
1HWD
1HWE
1HWF
1HWH
1HWI
|
|
gptkbp:postTranslationalModification
|
Phosphorylation
Disulfide bond
|
|
gptkbp:protein_name
|
Somatotropin
|
|
gptkbp:proteinFamily
|
PF00103
Somatotropin/prolactin family
|
|
gptkbp:Reactome
|
R-HSA-977443
R-HSA-6807249
|
|
gptkbp:RefSeq
|
NP_000506.2
|
|
gptkbp:sequenceStatus
|
Reviewed
|
|
gptkbp:signalPeptide
|
1-27
|
|
gptkbp:STRING_ID
|
9606.ENSP00000354587
|
|
gptkbp:subcellularLocation
|
Secreted
|
|
gptkbp:tissue_specificity
|
Pituitary gland
|
|
gptkbp:UniProtID
|
gptkb:P01270
|
|
gptkbp:bfsParent
|
gptkb:PTH
|
|
gptkbp:bfsLayer
|
6
|