|
gptkbp:instanceOf
|
gptkb:drug
benzodiazepine
|
|
gptkbp:ATCCode
|
N05BA04
|
|
gptkbp:availableOn
|
gptkb:tablet
many countries worldwide
capsule
|
|
gptkbp:bioavailability
|
>90%
|
|
gptkbp:brand
|
gptkb:Alepam
gptkb:Serax
Oxazepamum
|
|
gptkbp:CASNumber
|
604-75-1
|
|
gptkbp:cause
|
dependence
withdrawal symptoms
|
|
gptkbp:contraindication
|
gptkb:myasthenia_gravis
severe respiratory insufficiency
sleep apnea syndrome
|
|
gptkbp:developedBy
|
gptkb:diazepam
|
|
gptkbp:discoveredIn
|
1965
|
|
gptkbp:eliminationHalfLife
|
5–15 hours
|
|
gptkbp:excretion
|
renal
|
|
gptkbp:hasInChIKey
|
IZBXXGPGSFNEMN-UHFFFAOYSA-N
|
|
gptkbp:hasMolecularFormula
|
C15H11ClN2O2
|
|
gptkbp:hasSMILES
|
C1=CC=C(C=C1)C2=NC(=O)C3=C(C=C(C=C3)Cl)N2O
|
|
gptkbp:hasUNII
|
TQ6TUZ8U0O
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Oxazepam
|
|
gptkbp:isSchedule
|
IV (US Controlled Substances Act)
|
|
gptkbp:IUPACName
|
gptkb:7-chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one
|
|
gptkbp:KEGGID
|
D00433
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:listedOn
|
gptkb:World_Health_Organization's_List_of_Essential_Medicines
|
|
gptkbp:metabolism
|
gptkb:diazepam
gptkb:chlordiazepoxide
gptkb:temazepam
hepatic
|
|
gptkbp:molecularWeight
|
286.71 g/mol
|
|
gptkbp:pregnancyCategory
|
D (US)
|
|
gptkbp:proteinBinding
|
>95%
|
|
gptkbp:PubChem_CID
|
CHEMBL651
4615
4455
DB00842
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
dizziness
fatigue
drowsiness
impaired coordination
|
|
gptkbp:usedFor
|
insomnia
anxiety disorders
alcohol withdrawal
|
|
gptkbp:bfsParent
|
gptkb:N05BA
|
|
gptkbp:bfsLayer
|
7
|