Statements (29)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:abbreviation |
BGLAP
|
gptkbp:affects |
testosterone production
muscle function |
gptkbp:alternativeName |
bone gamma-carboxyglutamic acid-containing protein
|
gptkbp:binds |
hydroxyapatite
|
gptkbp:contains |
gamma-carboxyglutamic acid residues
|
gptkbp:discoveredBy |
L. G. Raisz
|
gptkbp:discoveredIn |
1975
|
gptkbp:encodedBy |
BGLAP gene
|
gptkbp:foundIn |
gptkb:bone
|
gptkbp:function |
hormone activity
regulation of bone mineralization |
gptkbp:halfLife |
5 minutes (in plasma)
|
https://www.w3.org/2000/01/rdf-schema#label |
Osteocalcin
|
gptkbp:influenced |
energy metabolism
insulin secretion |
gptkbp:locatedOnChromosome |
gptkb:chromosome_1q22
|
gptkbp:measures |
serum
|
gptkbp:molecularWeight |
5.6 kDa
|
gptkbp:presentIn |
vertebrates
|
gptkbp:producedBy |
osteoblasts
|
gptkbp:regulates |
gptkb:vitamin_A
vitamin D |
gptkbp:significance |
osteoporosis marker
|
gptkbp:structure |
single-chain polypeptide
|
gptkbp:usedAs |
biomarker for bone formation
|
gptkbp:bfsParent |
gptkb:Calcitonin
|
gptkbp:bfsLayer |
5
|