Zofran

GPTKB entity

Statements (39)
Predicate Object
gptkbp:instanceOf gptkb:drug
gptkbp:approvedBy gptkb:FDA
1991
gptkbp:ATCCode gptkb:A04AA01
gptkbp:availableOn gptkb:brand
generic
gptkbp:contraindication hypersensitivity to ondansetron
gptkbp:drugClass antiemetic
gptkbp:eliminationHalfLife 3-6 hours
gptkbp:excretion urine
feces
gptkbp:form gptkb:tablet
solution for injection
oral disintegrating tablet
gptkbp:genericName gptkb:ondansetron
https://www.w3.org/2000/01/rdf-schema#label Zofran
gptkbp:indication chemotherapy-induced nausea and vomiting
postoperative nausea and vomiting
radiotherapy-induced nausea and vomiting
gptkbp:interactsWith other serotonergic drugs
apomorphine
gptkbp:legalStatus prescription only
gptkbp:manufacturer GlaxoSmithKline
gptkbp:mechanismOfAction serotonin 5-HT3 receptor antagonist
gptkbp:metabolism liver
gptkbp:pregnancyCategory B (US)
gptkbp:riskFactor gptkb:serotonin_syndrome
QT prolongation
gptkbp:routeOfAdministration oral
intramuscular
intravenous
gptkbp:sideEffect constipation
dizziness
fatigue
headache
gptkbp:usedFor nausea
vomiting
gptkbp:bfsParent gptkb:Novartis
gptkbp:bfsLayer 4