Nuedexta (with quinidine)

URI: https://gptkb.org/entity/Nuedexta_(with_quinidine)
GPTKB entity
Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:drug
gptkbp:activeIngredient gptkb:dextromethorphan
quinidine
gptkbp:approvalYear 2010
gptkbp:approvedBy gptkb:FDA
gptkbp:ATCCode N07XX59
gptkbp:contraindication heart failure
prolonged QT interval
concomitant use with MAO inhibitors
gptkbp:dextromethorphanDosePerCapsule 20 mg
gptkbp:drugClass antiarrhythmic (quinidine component)
antitussive combination
gptkbp:form capsule
https://www.w3.org/2000/01/rdf-schema#label Nuedexta (with quinidine)
gptkbp:indication neurological disorders with emotional lability
gptkbp:legalStatus prescription only
gptkbp:manufacturer gptkb:Avanir_Pharmaceuticals
gptkbp:mechanismOfAction NMDA receptor antagonist
sigma-1 receptor agonist
CYP2D6 inhibitor (via quinidine)
gptkbp:pregnancyCategory C (US)
gptkbp:prescribes amyotrophic lateral sclerosis (ALS) with pseudobulbar affect
multiple sclerosis (MS) with pseudobulbar affect
gptkbp:quinidineDosePerCapsule 10 mg
gptkbp:routeOfAdministration oral
gptkbp:sideEffect diarrhea
dizziness
cough
peripheral edema
gptkbp:usedFor gptkb:pseudobulbar_affect
gptkbp:bfsParent gptkb:Dextromethorphan
gptkbp:bfsLayer 7