New Delhi Metallo-beta-lactamase
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:abbreviation |
gptkb:NDM
|
| gptkbp:cofactor |
zinc
|
| gptkbp:discoveredBy |
Yong et al.
|
| gptkbp:discoveredIn |
2008
|
| gptkbp:firstIsolatedFrom |
gptkb:Klebsiella_pneumoniae
|
| gptkbp:firstReported |
gptkb:Sweden
|
| gptkbp:foundIn |
gptkb:Enterobacteriaceae
gptkb:Pseudomonas_aeruginosa gptkb:Acinetobacter_baumannii |
| gptkbp:gene |
blaNDM
|
| https://www.w3.org/2000/01/rdf-schema#label |
New Delhi Metallo-beta-lactamase
|
| gptkbp:inhibitedBy |
none of the clinically available beta-lactamase inhibitors
|
| gptkbp:mechanismOfAction |
hydrolyzes beta-lactam antibiotics
|
| gptkbp:namedAfter |
gptkb:New_Delhi
|
| gptkbp:publicHealthConcern |
antibiotic resistance
|
| gptkbp:relatedTo |
IMP beta-lactamase
VIM beta-lactamase |
| gptkbp:resistantTo |
carbapenem antibiotics
|
| gptkbp:sequence |
metallo-beta-lactamase
|
| gptkbp:spreadTo |
horizontal gene transfer
|
| gptkbp:bfsParent |
gptkb:NDM
|
| gptkbp:bfsLayer |
8
|