|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:alternativeName
|
sialidase
|
|
gptkbp:antigen
|
gptkb:N11
gptkb:N1
gptkb:N8
gptkb:N10
gptkb:N9
N2
N3
N4
N5
N6
N7
|
|
gptkbp:component
|
gptkb:influenza_B_virus
gptkb:influenza_C_virus
gptkb:influenza
|
|
gptkbp:discoveredBy
|
gptkb:George_Hirst
|
|
gptkbp:EC_number
|
3.2.1.18
|
|
gptkbp:foundIn
|
gptkb:influenza_virus
|
|
gptkbp:function
|
cleaves sialic acid residues
|
|
gptkbp:gene
|
NA gene
|
|
gptkbp:inhibitedBy
|
neuraminidase inhibitors
|
|
gptkbp:location
|
gptkb:viral_envelope
|
|
gptkbp:molecularWeight
|
~220 kDa (tetramer)
|
|
gptkbp:presentIn
|
orthomyxoviridae family
|
|
gptkbp:relatedTo
|
hemagglutinin (HA)
|
|
gptkbp:requires
|
virus infectivity
|
|
gptkbp:role
|
viral release
facilitating virus spread
preventing viral aggregation
|
|
gptkbp:structure
|
tetramer
|
|
gptkbp:substrate
|
sialic acid
|
|
gptkbp:target
|
gptkb:laninamivir
gptkb:oseltamivir
gptkb:zanamivir
peramivir
|
|
gptkbp:usedFor
|
antiviral drug development
diagnosis of influenza
|
|
gptkbp:usedIn
|
subtyping influenza viruses
|
|
gptkbp:bfsParent
|
gptkb:Influenza_Virus
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Neuraminidase (NA)
|