Neuraminidase (NA)

GPTKB entity

Statements (42)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:alternativeName sialidase
gptkbp:antigen gptkb:N11
gptkb:N1
gptkb:N8
gptkb:N10
gptkb:N9
N2
N3
N4
N5
N6
N7
gptkbp:component gptkb:influenza_B_virus
gptkb:influenza_C_virus
influenza
gptkbp:discoveredBy gptkb:George_Hirst
gptkbp:EC_number 3.2.1.18
gptkbp:foundIn gptkb:influenza_virus
gptkbp:function cleaves sialic acid residues
gptkbp:gene NA gene
https://www.w3.org/2000/01/rdf-schema#label Neuraminidase (NA)
gptkbp:inhibitedBy neuraminidase inhibitors
gptkbp:location viral envelope
gptkbp:molecularWeight ~220 kDa (tetramer)
gptkbp:presentIn orthomyxoviridae family
gptkbp:relatedTo hemagglutinin (HA)
gptkbp:requires virus infectivity
gptkbp:role viral release
facilitating virus spread
preventing viral aggregation
gptkbp:structure tetramer
gptkbp:substrate sialic acid
gptkbp:target gptkb:laninamivir
gptkb:oseltamivir
gptkb:zanamivir
peramivir
gptkbp:usedFor antiviral drug development
diagnosis of influenza
gptkbp:usedIn subtyping influenza viruses
gptkbp:bfsParent gptkb:Influenza_Virus
gptkbp:bfsLayer 6