gptkbp:instance_of
|
gptkb:drug
|
gptkbp:bfsLayer
|
4
|
gptkbp:bfsParent
|
gptkb:virus
|
gptkbp:activities
|
neuraminidase inhibitor
|
gptkbp:approves
|
gptkb:legislation
gptkb:1999
gptkb:FDA
gptkb:United_States
|
gptkbp:availability
|
prescription only
|
gptkbp:brand
|
gptkb:Oseltamivir_phosphate
gptkb:Tamiflu
|
gptkbp:children
|
approved for children over 1 year
|
gptkbp:clinical_trial
|
80% to 90%
NC T00003059
NC T00120280
NC T00206300
NC T00313480
NC T00400001
|
gptkbp:composed_of
|
from oseltamivir carboxylate
from shikimic acid
|
gptkbp:contraindication
|
hypersensitivity to oseltamivir
|
gptkbp:developed_by
|
gptkb:Gilead_Sciences
|
gptkbp:dosage_form
|
gptkb:beer
suspension
|
gptkbp:excretion
|
urine
|
https://www.w3.org/2000/01/rdf-schema#label
|
oseltamivir
|
gptkbp:indication
|
prophylaxis of influenza
|
gptkbp:ingredients
|
C16 H28 N2 O4 S
|
gptkbp:interacts_with
|
live attenuated influenza vaccine
probenecid
|
gptkbp:is_atype_of
|
J05 A H02
|
gptkbp:is_effective_against
|
reduces duration of flu symptoms
reduces risk of flu complications
|
gptkbp:is_used_by
|
caution advised
|
gptkbp:is_used_for
|
treatment of influenza
dose adjustment required
|
gptkbp:lifespan
|
1 to 2 hours
|
gptkbp:manager
|
oral
|
gptkbp:marketed_as
|
gptkb:Tamiflu
|
gptkbp:metabolism
|
liver
|
gptkbp:safety_features
|
C during pregnancy
|
gptkbp:shelf_life
|
2 years
|
gptkbp:side_effect
|
headache
nausea
vomiting
diarrhea
|
gptkbp:storage
|
room temperature
|
gptkbp:suitable_for
|
gptkb:CDC
gptkb:WHO
|
gptkbp:type_of
|
198470-85-8
|