Neonatal Diabetes Mellitus

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:disease gptkb:form_of_diabetes_mellitus
gptkbp:can_be_familial	yes
gptkbp:can_be_permanent	yes
gptkbp:can_be_sporadic	yes
gptkbp:can_be_transient	yes
gptkbp:can_relapse	yes (in transient form)
gptkbp:can_remit	yes (in transient form)
gptkbp:cause	genetic mutations
gptkbp:complication	gptkb:intellectual_disability seizures developmental delay
gptkbp:diagnosedBy	genetic testing blood glucose test
gptkbp:differentialDiagnosis	gptkb:type_1_diabetes_mellitus
gptkbp:firstDescribed	1950s
gptkbp:gene	gptkb:INS KCNJ11 ABCC8
gptkbp:has_onset	within first 6 months of life
gptkbp:ICD-10_code	E10-E14
gptkbp:inheritance	autosomal dominant autosomal recessive
gptkbp:mayPresentWith	vomiting respiratory distress congenital heart defects jaundice lethargy hepatomegaly macroglossia glycosuria umbilical hernia polyuria ketoacidosis intrauterine growth retardation
gptkbp:MeSH_ID	D053684
gptkbp:not_related_to	autoimmune diabetes
gptkbp:OMIM	606176
gptkbp:prevalence	rare
gptkbp:relatedTo	gptkb:monogenic_diabetes
gptkbp:riskFactor	family history of diabetes
gptkbp:symptom	weight loss dehydration failure to thrive hyperglycemia
gptkbp:treatment	gptkb:insulin sulfonylureas
gptkbp:bfsParent	gptkb:D004053
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	Neonatal Diabetes Mellitus