Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
autoimmune disease |
| gptkbp:affects |
adults
children |
| gptkbp:affectsCellType |
beta cell
|
| gptkbp:affectsOrgan |
pancreas
|
| gptkbp:alsoKnownAs |
gptkb:juvenile_diabetes
insulin-dependent diabetes mellitus |
| gptkbp:cannotBePreventedBy |
lifestyle modification
|
| gptkbp:cause |
acute complications
chronic complications |
| gptkbp:causedBy |
autoimmune destruction of pancreatic beta cells
|
| gptkbp:complication |
gptkb:cardiovascular_disease
gptkb:hypoglycemia gptkb:diabetic_ketoacidosis gptkb:nephropathy peripheral neuropathy retinopathy |
| gptkbp:diagnosedBy |
blood glucose test
C-peptide test autoantibody test |
| gptkbp:firstDescribed |
19th century
|
| gptkbp:hasGlobalPrevalence |
~9% of all diabetes cases
|
| gptkbp:hasIncidencePeak |
puberty
early adulthood |
| gptkbp:hasMortalityRisk |
increased if untreated
|
| gptkbp:hasNoCure |
true
|
| https://www.w3.org/2000/01/rdf-schema#label |
type 1 diabetes mellitus
|
| gptkbp:ICD-10_code |
E10
|
| gptkbp:MeSH_ID |
gptkb:D003922
|
| gptkbp:OMIM |
222100
|
| gptkbp:onset |
childhood
adolescence |
| gptkbp:prevalence |
less common than type 2 diabetes
|
| gptkbp:requiresLifelongTreatment |
true
|
| gptkbp:requiresMonitoring |
blood glucose
|
| gptkbp:result |
insulin deficiency
|
| gptkbp:riskFactor |
family history
genetic predisposition environmental factors |
| gptkbp:symptom |
fatigue
blurred vision frequent urination increased thirst unintended weight loss |
| gptkbp:treatment |
blood glucose monitoring
insulin therapy diet management |
| gptkbp:bfsParent |
gptkb:SGLT2_inhibitors
gptkb:Steglujan gptkb:Galvus_Met |
| gptkbp:bfsLayer |
6
|