Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:voltage-gated_potassium_channel
|
| gptkbp:alias |
gptkb:Nav1.6
Sodium channel, voltage-gated, type VIII, alpha subunit |
| gptkbp:associatedWith |
epilepsy
ataxia |
| gptkbp:discoveredBy |
William A. Catterall
|
| gptkbp:encodedBy |
SCN8A gene
|
| gptkbp:expressedIn |
central nervous system
nodes of Ranvier |
| gptkbp:firstDescribed |
1995
|
| gptkbp:foundIn |
neurons
|
| gptkbp:function |
action potential propagation
|
| https://www.w3.org/2000/01/rdf-schema#label |
NaV1.6
|
| gptkbp:locatedOnChromosome |
chromosome 12q13
|
| gptkbp:modulatedBy |
phosphorylation
auxiliary beta subunits |
| gptkbp:molecularWeight |
~260 kDa
|
| gptkbp:mutationAssociatedWith |
neurological disorders
|
| gptkbp:species |
gptkb:human
gptkb:mouse right |
| gptkbp:subunit |
alpha subunit
|
| gptkbp:YouTubeChannel |
gptkb:voltage-gated_potassium_channel
|
| gptkbp:bfsParent |
gptkb:SCN8A
|
| gptkbp:bfsLayer |
7
|