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gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
hNTH1
nth homolog 1
|
|
gptkbp:associatedWith
|
gptkb:MUTYH
gptkb:OGG1
colorectal cancer
NTHL1 tumor syndrome
|
|
gptkbp:biologicalProcess
|
DNA N-glycosylase activity
AP lyase activity
|
|
gptkbp:discoveredIn
|
1997
|
|
gptkbp:Entrez_Gene_ID
|
4913
ENSG00000132780
|
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gptkbp:expressedIn
|
ubiquitous
|
|
gptkbp:fullName
|
nth endonuclease III-like 1
|
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gptkbp:function
|
DNA glycosylase involved in base excision repair
removes oxidized pyrimidines from DNA
|
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gptkbp:geneType
|
protein-coding
|
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gptkbp:GOID
|
GO:0006284
GO:0004519
|
|
gptkbp:HGNC_ID
|
7897
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NTHL1
|
|
gptkbp:length
|
312 amino acids
|
|
gptkbp:locatedOnChromosome
|
16p13.3
|
|
gptkbp:location
|
gptkb:nucleus
|
|
gptkbp:mutationAssociatedWith
|
biallelic mutations cause predisposition to multiple tumor types
|
|
gptkbp:OMIM
|
602656
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
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gptkbp:orthologIn
|
nth (E. coli)
|
|
gptkbp:pathway
|
base excision repair
|
|
gptkbp:product
|
Endonuclease III-like protein 1
|
|
gptkbp:UniProtID
|
Q7KZ85
|
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gptkbp:bfsParent
|
gptkb:chromosome_16p13.3
gptkb:16p13.13
|
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gptkbp:bfsLayer
|
7
|