NTCP (sodium taurocholate co-transporting polypeptide)
GPTKB entity
Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:SLC10A1
gptkb:solute_carrier_family_10_member_1 |
| gptkbp:encodedBy |
gptkb:SLC10A1_gene
|
| gptkbp:expressedIn |
gptkb:hepatocytes
|
| gptkbp:function |
bile acid transporter
sodium-dependent bile acid uptake |
| https://www.w3.org/2000/01/rdf-schema#label |
NTCP (sodium taurocholate co-transporting polypeptide)
|
| gptkbp:inhibitedBy |
gptkb:myrcludex_B
|
| gptkbp:locatedIn |
liver
|
| gptkbp:locatedOnChromosome |
14q24.1
|
| gptkbp:molecularWeight |
~56 kDa
|
| gptkbp:mutationAssociatedWith |
bile acid malabsorption
hypercholanemia |
| gptkbp:OMIM |
600214
|
| gptkbp:requires |
enterohepatic circulation of bile acids
|
| gptkbp:significance |
receptor for hepatitis B virus
receptor for hepatitis D virus |
| gptkbp:species |
gptkb:human
|
| gptkbp:structure |
transmembrane protein
|
| gptkbp:transmembraneDomains |
7
yes |
| gptkbp:transportation |
gptkb:taurocholate
bile acids conjugated bile salts |
| gptkbp:UniProtID |
gptkb:Q14973
|
| gptkbp:bfsParent |
gptkb:bulevirtide
|
| gptkbp:bfsLayer |
7
|