Properties (57)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
protein
|
| gptkbp:alcoholContent |
transcription factors
crystal structure available |
| gptkbp:associatedWith |
transcription factors
|
| gptkbp:castMember |
RNA_polymerase_II
|
| gptkbp:clinicalTrials |
ongoing clinical trials
biomarker for prognosis |
| gptkbp:community |
various tissues
upregulated in cancer regulated by signaling pathways |
| gptkbp:culturalEvents |
NSR-REP1_in_other_species
|
| gptkbp:diseaseResistance |
associated with various cancers
|
| gptkbp:evaluates |
RT-qPCR
|
| gptkbp:fauna |
Homo sapiens
|
| gptkbp:fossilRecord |
biological process
|
| gptkbp:function |
regulates gene expression
|
| gptkbp:geneticDiversity |
chromosome 1
loss of function highly conserved across species NSR1 mouse_model_available |
| gptkbp:hasLocation |
nuclear speckles
|
| https://www.w3.org/2000/01/rdf-schema#label |
NSR-REP1
|
| gptkbp:interactsWith |
DNA
small molecules protein-protein interaction |
| gptkbp:internationalClassification |
C2H2 zinc finger proteins
|
| gptkbp:involvedIn |
cellular response to stress
|
| gptkbp:is_a_promoter_of |
plasmid available
|
| gptkbp:is_a_route_for |
cell cycle regulation
|
| gptkbp:isActiveIn |
specific inhibitors
|
| gptkbp:isCompatibleWith |
stabilized by chaperones
|
| gptkbp:localAttraction |
localized to the nucleus
|
| gptkbp:location |
nucleus
|
| gptkbp:naturalResources |
available in databases
|
| gptkbp:operations |
E. coli
|
| gptkbp:originalNetwork |
mapped in interactome studies
|
| gptkbp:participatesIn |
cancer
|
| gptkbp:postRetirementCareer |
phosphorylation
|
| gptkbp:primaryFunction |
involved in transcriptional activation
luciferase reporter assay |
| gptkbp:productLine |
studied in various cancer cell lines
|
| gptkbp:regulatoryCompliance |
promoter region
regulates cellular processes |
| gptkbp:relatedTo |
gene regulation
|
| gptkbp:releaseYear |
2005
|
| gptkbp:research |
funded_by_NIH
|
| gptkbp:research_areas |
potential target for therapy
|
| gptkbp:researchField |
molecular biology
|
| gptkbp:researchInterest |
published in peer-reviewed journals
gene knockout target for drug development |
| gptkbp:supportRole |
modulates transcriptional activity
|
| gptkbp:technologyDomain |
zinc finger domain
DNA-binding domain |
| gptkbp:type |
transcriptional regulator
|
| gptkbp:weight |
approximately 50 kDa
|