NRTI

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf antiretroviral therapy
gptkbp:administeredBy oral route
gptkbp:approvedBy gptkb:FDA
1987
gptkbp:category nucleoside analogues
nucleotide analogues
gptkbp:combines PI
INSTI
NNRTI
gptkbp:drugClass antiviral drugs
gptkbp:example gptkb:abacavir
gptkb:lamivudine
gptkb:zidovudine
emtricitabine
tenofovir
gptkbp:hasApprovedDrug gptkb:zidovudine
https://www.w3.org/2000/01/rdf-schema#label NRTI
gptkbp:mechanismOfAction inhibits reverse transcriptase
gptkbp:sideEffect gptkb:anemia
peripheral neuropathy
lactic acidosis
hepatic steatosis
gptkbp:standsFor Nucleoside Reverse Transcriptase Inhibitor
gptkbp:target gptkb:HIV-1
gptkb:HIV-2
gptkbp:usedFor HIV treatment
gptkbp:bfsParent gptkb:zalcitabine
gptkbp:bfsLayer 6