|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:discoveredBy
|
gptkb:Albert_Szent-Györgyi
|
|
gptkbp:discoveredIn
|
1940s
|
|
gptkbp:domain
|
coiled-coil domain
motor domain
tail domain
|
|
gptkbp:encodedBy
|
MYH gene family
|
|
gptkbp:formsComplexWith
|
myosin light chain
|
|
gptkbp:foundIn
|
gptkb:skeletal_muscle
|
|
gptkbp:function
|
ATPase activity
motor activity
|
|
gptkbp:GOProcess
|
GO:0006936 (muscle contraction)
|
|
gptkbp:hasComponent
|
GO:0005859 (muscle myosin complex)
|
|
gptkbp:hasGOFunction
|
GO:0003774 (motor activity)
GO:0016459 (myosin complex)
|
|
gptkbp:hasIsoform
|
gptkb:MYH11
gptkb:MYH7
gptkb:MYH10
MYH2
MYH6
MYH1
MYH13
MYH14
MYH3
MYH4
MYH8
MYH9
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Myosin heavy chain
|
|
gptkbp:involvedIn
|
muscle contraction
|
|
gptkbp:location
|
gptkb:cytoplasm
|
|
gptkbp:molecularWeight
|
~220 kDa
|
|
gptkbp:mutationAssociatedWith
|
muscular dystrophy
cardiomyopathies
myopathies
|
|
gptkbp:orthologIn
|
gptkb:human
gptkb:meat
gptkb:mouse
gptkb:zebrafish
right
|
|
gptkbp:partOf
|
gptkb:myosin
|
|
gptkbp:PDB
|
5TBY
1DFL
2MYS
|
|
gptkbp:presentIn
|
gptkb:skeletal_muscle
cardiac muscle
smooth muscle
|
|
gptkbp:studiedIn
|
biochemistry
cell biology
muscle physiology
|
|
gptkbp:bfsParent
|
gptkb:Mhc_(Drosophila_melanogaster)
|
|
gptkbp:bfsLayer
|
7
|