Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
protein scaffold
|
| gptkbp:advantage |
stability
solubility ease of production |
| gptkbp:alternativeTo |
gptkb:monoclonal_antibody
|
| gptkbp:basedOn |
fibronectin type III domain
|
| gptkbp:bindingAffinity |
high
|
| gptkbp:canBe |
gptkb:yeast
gptkb:Bacteria structural biology therapeutic targeting mammalian cells protein detection protein inhibition |
| gptkbp:developedBy |
Shohei Koide
|
| gptkbp:engineeredFor |
target specificity
|
| gptkbp:firstDescribed |
2004
|
| gptkbp:hasNo |
disulfide bonds
|
| https://www.w3.org/2000/01/rdf-schema#label |
Monobody
|
| gptkbp:origin |
fibronectin type III domain of human fibronectin
|
| gptkbp:patent |
gptkb:New_York_University
gptkb:University_of_Chicago |
| gptkbp:relatedTo |
Adnectin
Affibody DARPins antibody mimetic |
| gptkbp:size |
~10 kDa
|
| gptkbp:structure |
beta-sandwich fold
|
| gptkbp:usedIn |
gptkb:biotechnology
research therapeutics |
| gptkbp:bfsParent |
gptkb:Nnamdi_Ogbonnaya
|
| gptkbp:bfsLayer |
8
|