Monoamine oxidase inhibitors
GPTKB entity
Statements (45)
Predicate | Object |
---|---|
gptkbp:instance_of |
gptkb:drug
|
gptkbp:bfsLayer |
4
|
gptkbp:bfsParent |
gptkb:Claritin-D
|
gptkbp:activities |
inhibition of monoamine oxidase enzyme
|
gptkbp:affects |
increase in dopamine levels
increase in norepinephrine levels increase in serotonin levels |
gptkbp:availability |
generic and brand names
|
gptkbp:class |
MAO Is
|
gptkbp:contraindication |
certain medications
certain foods high in tyramine |
gptkbp:discovered_by |
by researchers in the 1950s
|
gptkbp:example |
gptkb:Isocarboxazid
gptkb:Phenelzine gptkb:Selegiline gptkb:Tranylcypromine |
gptkbp:first_introduced |
1950s
|
https://www.w3.org/2000/01/rdf-schema#label |
Monoamine oxidase inhibitors
|
gptkbp:interacts_with |
antidepressants
opioids stimulants serotonin syndrome |
gptkbp:is_used_for |
treatment of anxiety disorders
treatment of depression |
gptkbp:notable_for |
in attention deficit hyperactivity disorder
in atypical depression in binge eating disorder in bulimia nervosa in chronic fatigue syndrome in chronic pain management in fibromyalgia in migraine prevention in obsessive-compulsive disorder in panic disorder in post-traumatic stress disorder in seasonal affective disorder in social anxiety disorder in treatment-resistant depression |
gptkbp:regulatory_compliance |
prescription medication
|
gptkbp:research |
ongoing studies on efficacy
|
gptkbp:side_effect |
dizziness
dry mouth weight gain hypertensive crisis |
gptkbp:targets |
neurotransmitters
|