Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:associatedWith |
gptkb:Charcot-Marie-Tooth_disease_type_2A
|
| gptkbp:encodedBy |
MFN2 gene
|
| gptkbp:expressedIn |
gptkb:skeletal_muscle
neuronal tissue |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
mitochondrial fusion
regulation of mitochondrial morphology mitochondrial tethering |
| https://www.w3.org/2000/01/rdf-schema#label |
Mitofusin-2 protein
|
| gptkbp:interactsWith |
Mitofusin-1 protein
|
| gptkbp:location |
outer mitochondrial membrane
|
| gptkbp:molecularWeight |
about 86 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:hereditary_spastic_paraplegia
peripheral neuropathy |
| gptkbp:OMIM |
608507
|
| gptkbp:regulates |
apoptosis
mitochondrial metabolism endoplasmic reticulum-mitochondria tethering mitochondrial network architecture |
| gptkbp:structure |
contains GTPase domain
contains coiled-coil domains |
| gptkbp:UniProtID |
O95140
|
| gptkbp:bfsParent |
gptkb:MFN2
|
| gptkbp:bfsLayer |
7
|