Methemoglobinemia

GPTKB entity

Statements (55)
Predicate Object
gptkbp:instanceOf gptkb:disease
gptkbp:affects adults
blood
infants
gptkbp:canBeLifeThreatening yes
gptkbp:cause gptkb:dapsone
gptkb:phenazopyridine
gptkb:primaquine
gptkb:hypoxia
antimalarial drugs
nitrites
neurological symptoms
phenacetin
death (in severe cases)
sulfonamides
chloroquine
nitrobenzene
benzocaine
chocolate-brown colored blood
hereditary enzyme deficiency
local anesthetics
nitrate-contaminated water
reduced oxygen delivery
gptkbp:causedBy nitrates
aniline dyes
certain drugs
exposure to oxidizing agents
gptkbp:characterizedBy elevated methemoglobin levels
gptkbp:diagnosedBy blood test
co-oximetry
gptkbp:firstDescribed 1845
gptkbp:hereditaryForm gptkb:hemoglobin_M_disease
cytochrome b5 reductase deficiency
https://www.w3.org/2000/01/rdf-schema#label Methemoglobinemia
gptkbp:ICD-10_code D74
gptkbp:inheritance yes
gptkbp:inheritedFormCausedBy genetic mutations
gptkbp:MeSH_ID gptkb:D008766
gptkbp:obtainedFrom yes
gptkbp:OMIM 250800
gptkbp:prevalence rare
gptkbp:prevention avoiding oxidizing agents
monitoring at-risk patients
gptkbp:symptom gptkb:arrhythmia
cyanosis
dizziness
fatigue
headache
shortness of breath
seizures
gptkbp:treatment gptkb:methylene_blue
ascorbic acid
oxygen therapy
gptkbp:bfsParent gptkb:hemoglobin
gptkbp:bfsLayer 5