Metastatic Breast Cancer

GPTKB entity

Statements (51)
Predicate Object
gptkbp:instanceOf gptkb:disease
gptkbp:affects Women
Men
gptkbp:alsoKnownAs Stage IV Breast Cancer
gptkbp:awarenessMonth October
gptkbp:canBeTripleNegative Yes
gptkbp:characterizedBy Spread of cancer cells beyond the breast
gptkbp:complication Pleural effusion
Liver failure
Brain metastases
Pathological fractures
gptkbp:diagnosedBy Biopsy
Imaging tests
gptkbp:firstDescribed 19th century
gptkbp:goalOfTreatment Palliation
Prolonging life
https://www.w3.org/2000/01/rdf-schema#label Metastatic Breast Cancer
gptkbp:ICD-10_code C50 with secondary codes
gptkbp:incidence Hundreds of thousands of cases worldwide annually
gptkbp:marking gptkb:Estrogen_receptor
gptkb:Progesterone_receptor
HER2
gptkbp:primaryTreatment gptkb:Systemic_Therapy
gptkbp:prognosis Generally incurable
Variable survival rates
gptkbp:researchInterest Improving quality of life
Developing new therapies
Extending survival
gptkbp:riskFactor Genetic mutations
Late-stage diagnosis
Previous breast cancer
gptkbp:spreadTo gptkb:Brain
gptkb:Bones
Lungs
Liver
gptkbp:subclassOf Breast Cancer
gptkbp:supportResource gptkb:American_Cancer_Society
gptkb:Susan_G._Komen_Foundation
Metastatic Breast Cancer Network
gptkbp:symptom Seizures
Shortness of breath
Jaundice
Bone pain
gptkbp:treatmentOption Radiation Therapy
Surgery
immunotherapy
Chemotherapy
Targeted Therapy
Hormone Therapy
gptkbp:bfsParent gptkb:NCT00239681
gptkbp:bfsLayer 7