Statements (50)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:disease
|
gptkbp:abbreviation |
gptkb:GVHD
|
gptkbp:affects |
gptkb:skin
gastrointestinal tract liver mucous membranes |
gptkbp:canBeAcute |
yes
|
gptkbp:canBeChronic |
yes
|
gptkbp:cause |
allogeneic tissue transplant
donor immune cells attacking recipient tissues |
gptkbp:complication |
hematopoietic stem cell transplantation
solid organ transplantation |
gptkbp:diagnosedBy |
laboratory tests
clinical evaluation biopsy |
gptkbp:firstDescribed |
1950s
|
gptkbp:hasType |
acute GVHD
chronic GVHD |
https://www.w3.org/2000/01/rdf-schema#label |
Graft-versus-host Disease
|
gptkbp:ICD-10_code |
T86.0
|
gptkbp:MeSH_ID |
gptkb:D005778
|
gptkbp:mortalityRate |
high in severe cases
|
gptkbp:namedFor |
Ray D. Owen
|
gptkbp:OMIM |
611194
|
gptkbp:prevention |
immunosuppressive drugs
HLA matching |
gptkbp:relatedTo |
autoimmune disease
transplant rejection |
gptkbp:riskFactor |
blood transfusion
bone marrow transplant stem cell transplant |
gptkbp:specialty |
immunology
oncology hematology |
gptkbp:symptom |
diarrhea
abdominal pain jaundice rash dry mouth liver dysfunction skin changes |
gptkbp:treatment |
gptkb:cyclosporine
gptkb:antithymocyte_globulin gptkb:tacrolimus gptkb:methotrexate immunosuppressive therapy corticosteroids extracorporeal photopheresis |
gptkbp:bfsParent |
gptkb:Cell_Therapy
|
gptkbp:bfsLayer |
6
|