Graft-versus-host Disease

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:disease
gptkbp:abbreviation gptkb:GVHD
gptkbp:affects gptkb:skin
gastrointestinal tract
liver
mucous membranes
gptkbp:canBeAcute yes
gptkbp:canBeChronic yes
gptkbp:cause allogeneic tissue transplant
donor immune cells attacking recipient tissues
gptkbp:complication hematopoietic stem cell transplantation
solid organ transplantation
gptkbp:diagnosedBy laboratory tests
clinical evaluation
biopsy
gptkbp:firstDescribed 1950s
gptkbp:hasType acute GVHD
chronic GVHD
https://www.w3.org/2000/01/rdf-schema#label Graft-versus-host Disease
gptkbp:ICD-10_code T86.0
gptkbp:MeSH_ID gptkb:D005778
gptkbp:mortalityRate high in severe cases
gptkbp:namedFor Ray D. Owen
gptkbp:OMIM 611194
gptkbp:prevention immunosuppressive drugs
HLA matching
gptkbp:relatedTo autoimmune disease
transplant rejection
gptkbp:riskFactor blood transfusion
bone marrow transplant
stem cell transplant
gptkbp:specialty immunology
oncology
hematology
gptkbp:symptom diarrhea
abdominal pain
jaundice
rash
dry mouth
liver dysfunction
skin changes
gptkbp:treatment gptkb:cyclosporine
gptkb:antithymocyte_globulin
gptkb:tacrolimus
gptkb:methotrexate
immunosuppressive therapy
corticosteroids
extracorporeal photopheresis
gptkbp:bfsParent gptkb:Cell_Therapy
gptkbp:bfsLayer 6