Melatonin

GPTKB entity

Statements (51)
Predicate Object
gptkbp:instanceOf hormone
neurotransmitter
gptkbp:ATCCode N05CH01
gptkbp:CASNumber 73-31-4
gptkbp:category antioxidant
chronobiotic
indoleamine
gptkbp:chemicalFormula C13H16N2O2
gptkbp:color white to off-white
gptkbp:discoveredBy gptkb:Aaron_B._Lerner
gptkbp:discoveredIn 1958
gptkbp:excretion urine
gptkbp:foundIn gptkb:Bacteria
animals
fungi
plants
gptkbp:halfLife 20–50 minutes
https://www.w3.org/2000/01/rdf-schema#label Melatonin
gptkbp:IUPACName gptkb:N-acetyl-5-methoxytryptamine
gptkbp:legalStatus over-the-counter (US)
prescription-only (EU)
gptkbp:meltingPoint 116–118 °C
gptkbp:MeSH_ID gptkb:D008545
gptkbp:metabolism liver
gptkbp:molecularWeight 232.278 g/mol
gptkbp:predecessor serotonin
tryptophan
gptkbp:producedBy pineal gland
gptkbp:PubChem_CID gptkb:CHEBI:16796
gptkb:CHEMBL941
896
gptkbp:recipient gptkb:MT1_receptor
gptkb:MT2_receptor
gptkb:MT3_receptor
gptkbp:regulates circadian rhythm
sleep-wake cycle
gptkbp:routeOfAdministration oral
transdermal
sublingual
gptkbp:sideEffect nausea
dizziness
headache
drowsiness
gptkbp:solubility slightly soluble in water
gptkbp:UNII JL5DK93RCL
gptkbp:usedAs dietary supplement
gptkbp:usedFor delayed sleep phase disorder
insomnia treatment
jet lag
gptkbp:bfsParent gptkb:Insomnia
gptkbp:bfsLayer 5