MYOG gene

GPTKB entity

Statements (47)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alias gptkb:MRF4
bHLHc3
myf4
gptkbp:biologicalProcess skeletal muscle tissue development
gptkbp:discoveredIn 1990
gptkbp:encodes myogenin protein
gptkbp:Entrez_Gene_ID 4656
ENSG00000109063
gptkbp:expressedIn gptkb:skeletal_muscle
muscle regeneration
embryonic muscle development
gptkbp:family myogenic regulatory factors
gptkbp:fullName gptkb:myogenin
gptkbp:function regulation of muscle differentiation
gptkbp:GO_Cellular_Component gptkb:nucleus
gptkbp:GO_Molecular_Function DNA-binding transcription factor activity
gptkbp:hasPromoter E-box motif
gptkbp:HGNC_ID HGNC:7610
https://www.w3.org/2000/01/rdf-schema#label MYOG gene
gptkbp:interactsWith gptkb:MEF2C
gptkb:E12
gptkb:E47
gptkb:MYOD1
gptkbp:locatedOnChromosome 1q32.1
gptkbp:mutationAssociatedWith muscle development disorders
gptkbp:OMIM 159980
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInCat gptkb:MYOG
gptkbp:orthologInChicken gptkb:MYOG
gptkbp:orthologInCow gptkb:MYOG
gptkbp:orthologInDog gptkb:MYOG
gptkbp:orthologInFrog myog
gptkbp:orthologInFruitFly nautilus
gptkbp:orthologInMouse Myog
gptkbp:orthologInPig gptkb:MYOG
gptkbp:orthologInZebrafish myog
gptkbp:proteinFamily basic helix-loop-helix (bHLH) transcription factors
gptkbp:regulates myogenesis
muscle-specific gene expression
regulated by MEF2 family
upregulated by MYOD1
gptkbp:requires terminal differentiation of myoblasts
gptkbp:transcription_factor yes
gptkbp:UniProtID P15173
gptkbp:bfsParent gptkb:myogenin
gptkbp:bfsLayer 6