Properties (53)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gene
|
| gptkbp:alcoholContent |
myelin protein zero
|
| gptkbp:associatedWith |
gptkb:Charcot-Marie-Tooth_disease
neuropathy demyelination axon degeneration |
| gptkbp:breedingSeason |
muscle weakness
sensory loss protein-coding gene foot deformities gait abnormalities demyelinating neuropathy |
| gptkbp:clinicalTrials |
available for mutations
assessing patient outcomes evaluating drug efficacy important for nerve function investigating gene therapy approaches linked to hereditary neuropathies studying neuropathy treatments ongoing_for_CMT_therapies used_in_diagnosis_of_CMT |
| gptkbp:code |
myelin protein zero
|
| gptkbp:community |
high in peripheral nervous system
low in central nervous system |
| gptkbp:culturalEvents |
MPZ_in_other_species
|
| gptkbp:diseaseResistance |
CMT1A
CMT1B CMTX |
| gptkbp:function |
myelination of peripheral nerves
|
| gptkbp:geneticDiversity |
single nucleotide polymorphisms
copy number variations 1q22 causes demyelinating neuropathy immunoglobulin superfamily MPZ |
| https://www.w3.org/2000/01/rdf-schema#label |
MPZ gene
|
| gptkbp:interactsWith |
sodium channels
neurofascin contactin |
| gptkbp:is_a_route_for |
myelination pathway
neurodegeneration pathway |
| gptkbp:is_evaluated_by |
gptkb:Schwann_cells
|
| gptkbp:locatedIn |
chromosome 1
|
| gptkbp:previouslyKnownAs |
myelin protein zero gene
|
| gptkbp:researchFocus |
peripheral nerve diseases
myelin_sheath_integrity |
| gptkbp:researchInterest |
animal models
gene therapy genetic testing genome-wide association studies gene sequencing functional assays PCR analysis |