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gptkbp:instanceOf
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gptkb:protein
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gptkbp:alternativeName
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gptkb:SLC16A1
Monocarboxylate transporter 1
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gptkbp:associatedWith
|
cancer metabolism
lactic acidosis
exercise performance
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gptkbp:discoveredBy
|
P.J. Halestrap
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gptkbp:discoveredIn
|
1994
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gptkbp:encodedBy
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gptkb:SLC16A1
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gptkbp:family
|
solute carrier family 16
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gptkbp:foundIn
|
many tissues including muscle, brain, heart, and red blood cells
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gptkbp:fullName
|
Monocarboxylate transporter 1
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gptkbp:function
|
transports monocarboxylates such as lactate, pyruvate, and ketone bodies across cell membranes
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gptkbp:gene
|
gptkb:SLC16A1
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|
https://www.w3.org/2000/01/rdf-schema#label
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MCT1
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gptkbp:inhibitedBy
|
AR-C155858
AZD3965
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gptkbp:locatedOnChromosome
|
1p13.2
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gptkbp:location
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gptkb:plasma_membrane
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gptkbp:molecularWeight
|
54 kDa
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gptkbp:mutationAssociatedWith
|
can cause exercise-induced hyperinsulinemic hypoglycemia
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gptkbp:significance
|
target for cancer therapy
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gptkbp:species
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gptkb:human
gptkb:mouse
right
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gptkbp:structure
|
12 transmembrane domains
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gptkbp:UniProtID
|
P53985
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gptkbp:bfsParent
|
gptkb:SLC16A1
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gptkbp:bfsLayer
|
7
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