Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
gptkb:cancer
|
| gptkbp:compatibleWith |
normal somatic tissues
|
| gptkbp:database |
GeneCards: MAGE family
HGNC: MAGE family UniProt: MAGE family |
| gptkbp:discoveredIn |
melanoma
|
| gptkbp:domain |
MAGE homology domain
|
| gptkbp:expressedIn |
gptkb:testis
various tumors |
| gptkbp:firstDescribed |
1991
|
| gptkbp:fullName |
Melanoma Antigen Gene family proteins
|
| gptkbp:function |
gptkb:tumor_antigen
regulation of apoptosis regulation of cell cycle |
| https://www.w3.org/2000/01/rdf-schema#label |
MAGE family proteins
|
| gptkbp:involves |
immune evasion
tumor progression |
| gptkbp:locatedOnChromosome |
gptkb:X_chromosome
|
| gptkbp:numberOfGenes |
over 60 in humans
|
| gptkbp:orthologIn |
MAGE-like proteins in other species
|
| gptkbp:proteinFamily |
MAGE
|
| gptkbp:recognizedBy |
cytotoxic T lymphocytes
|
| gptkbp:subfamily |
MAGE-A
MAGE-B MAGE-C MAGE-D MAGE-E MAGE-F MAGE-G MAGE-H |
| gptkbp:usedIn |
immunotherapy
|
| gptkbp:bfsParent |
gptkb:tumor_antigen
|
| gptkbp:bfsLayer |
6
|