|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
|
|
gptkbp:compatibleWith
|
normal somatic tissues
|
|
gptkbp:database
|
GeneCards: MAGE family
HGNC: MAGE family
UniProt: MAGE family
|
|
gptkbp:discoveredIn
|
gptkb:melanoma
|
|
gptkbp:domain
|
MAGE homology domain
|
|
gptkbp:expressedIn
|
gptkb:testis
various tumors
|
|
gptkbp:firstDescribed
|
1991
|
|
gptkbp:fullName
|
Melanoma Antigen Gene family proteins
|
|
gptkbp:function
|
gptkb:tumor_antigen
regulation of apoptosis
regulation of cell cycle
|
|
gptkbp:involves
|
immune evasion
tumor progression
|
|
gptkbp:locatedOnChromosome
|
gptkb:X_chromosome
|
|
gptkbp:numberOfGenes
|
over 60 in humans
|
|
gptkbp:orthologIn
|
MAGE-like proteins in other species
|
|
gptkbp:proteinFamily
|
MAGE
|
|
gptkbp:recognizedBy
|
cytotoxic T lymphocytes
|
|
gptkbp:subfamily
|
MAGE-A
MAGE-B
MAGE-C
MAGE-D
MAGE-E
MAGE-F
MAGE-G
MAGE-H
|
|
gptkbp:usedIn
|
gptkb:immunotherapy
|
|
gptkbp:bfsParent
|
gptkb:tumor_antigen
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAGE family proteins
|