M-phase promoting factor (MPF)
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
Cdc25 phosphatase
cyclin accumulation |
| gptkbp:activeDuring |
gptkb:M_phase
|
| gptkbp:alsoKnownAs |
maturation-promoting factor
|
| gptkbp:composedOf |
gptkb:cyclin_B
gptkb:CDK1 |
| gptkbp:decommissioned |
cyclin degradation
|
| gptkbp:discoveredBy |
Yoshio Masui
Clement Markert |
| gptkbp:discoveredIn |
1971
Xenopus oocytes |
| gptkbp:function |
induces entry into mitosis
|
| gptkbp:GO_term |
GO:0031465
|
| https://www.w3.org/2000/01/rdf-schema#label |
M-phase promoting factor (MPF)
|
| gptkbp:inhibitedBy |
Wee1 kinase
|
| gptkbp:phosphorylates |
gptkb:condensin
lamin proteins microtubule-associated proteins |
| gptkbp:regulates |
cell cycle
|
| gptkbp:requires |
mitotic entry
meiotic entry |
| gptkbp:role |
chromosome condensation
nuclear envelope breakdown spindle assembly |
| gptkbp:species |
gptkb:Eukaryota
|
| gptkbp:bfsParent |
gptkb:cyclin_B1
gptkb:Cyclin_B |
| gptkbp:bfsLayer |
7
|