Lupus Erythematosus Systemicus

URI: https://gptkb.org/entity/Lupus_Erythematosus_Systemicus
GPTKB entity
Statements (53)
Predicate Object
gptkbp:instanceOf autoimmune disease
systemic disease
gptkbp:abbreviation SLE
gptkbp:affects gptkb:skin
brain
heart
lungs
kidneys
joints
gptkbp:alsoKnownAs gptkb:Systemic_Lupus_Erythematosus
gptkbp:autoantibody gptkb:ANA
gptkb:anti-La
gptkb:anti-Ro
gptkb:anti-Smith
gptkb:anti-dsDNA
gptkbp:cause gptkb:Raynaud's_phenomenon
unknown
alopecia
psychosis
pericarditis
seizures
thrombocytopenia
leukopenia
pleuritis
gptkbp:commonIn gptkb:women
gptkbp:complication gptkb:cardiovascular_disease
gptkb:anemia
stroke
infections
lupus nephritis
gptkbp:diagnosedBy gptkb:ANA_test
clinical criteria
anti-dsDNA test
gptkbp:firstDescribed 19th century
https://www.w3.org/2000/01/rdf-schema#label Lupus Erythematosus Systemicus
gptkbp:ICD-10_code gptkb:M32
gptkbp:prevalence 20-150 per 100,000 people
gptkbp:riskFactor genetic predisposition
female sex
age 15-45
ethnicity (African, Asian, Hispanic descent)
gptkbp:symptom fever
fatigue
joint pain
photosensitivity
skin rash
oral ulcers
gptkbp:treatment gptkb:NSAIDs
corticosteroids
immunosuppressants
antimalarials
gptkbp:bfsParent gptkb:LES
gptkbp:bfsLayer 6