Luciferase

GPTKB entity

Statements (51)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:discoveredBy gptkb:Raphaël_Dubois
gptkbp:discoveredIn 1885
gptkbp:EC_number 1.13.12.7
gptkbp:emissionColor blue (marine)
yellow-green (firefly)
gptkbp:emits visible light
gptkbp:foundIn gptkb:Bacteria
fungi
marine organisms
fireflies
gptkbp:function catalyzes oxidation of luciferin
gptkbp:gene luc
https://www.w3.org/2000/01/rdf-schema#label Luciferase
gptkbp:molecularWeight ~61 kDa (firefly luciferase)
gptkbp:produces bioluminescence
gptkbp:requires oxygen
gptkbp:structure heterodimeric (bacterial)
monomeric (firefly)
gptkbp:substrate luciferin
gptkbp:type oxidoreductase
gptkbp:usedAs reporter gene
gptkbp:usedFor bioluminescent imaging
cell viability assays
gene expression assays
protein-protein interaction assays
gptkbp:usedIn gptkb:biotechnology
CRISPR screening
biosensors
cancer research
molecular biology
forensic science
synthetic biology
environmental monitoring
food safety testing
toxicology studies
medical diagnostics
protein folding studies
transgenic organisms
cell signaling studies
gene therapy research
drug screening
antibiotic testing
RNA interference assays
apoptosis assays
pathogen detection
promoter activity assays
protein stability assays
viral infection assays
gptkbp:bfsParent gptkb:Fireflies
gptkbp:bfsLayer 5