Statements (51)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:enzyme
|
gptkbp:discoveredBy |
gptkb:Raphaël_Dubois
|
gptkbp:discoveredIn |
1885
|
gptkbp:EC_number |
1.13.12.7
|
gptkbp:emissionColor |
blue (marine)
yellow-green (firefly) |
gptkbp:emits |
visible light
|
gptkbp:foundIn |
gptkb:Bacteria
fungi marine organisms fireflies |
gptkbp:function |
catalyzes oxidation of luciferin
|
gptkbp:gene |
luc
|
https://www.w3.org/2000/01/rdf-schema#label |
Luciferase
|
gptkbp:molecularWeight |
~61 kDa (firefly luciferase)
|
gptkbp:produces |
bioluminescence
|
gptkbp:requires |
oxygen
|
gptkbp:structure |
heterodimeric (bacterial)
monomeric (firefly) |
gptkbp:substrate |
luciferin
|
gptkbp:type |
oxidoreductase
|
gptkbp:usedAs |
reporter gene
|
gptkbp:usedFor |
bioluminescent imaging
cell viability assays gene expression assays protein-protein interaction assays |
gptkbp:usedIn |
gptkb:biotechnology
CRISPR screening biosensors cancer research molecular biology forensic science synthetic biology environmental monitoring food safety testing toxicology studies medical diagnostics protein folding studies transgenic organisms cell signaling studies gene therapy research drug screening antibiotic testing RNA interference assays apoptosis assays pathogen detection promoter activity assays protein stability assays viral infection assays |
gptkbp:bfsParent |
gptkb:Fireflies
|
gptkbp:bfsLayer |
5
|