Low-density lipoprotein (LDL)

GPTKB entity

Predicate	Object
gptkbp:instanceOf	lipoprotein
gptkbp:abbreviation	gptkb:LDL
gptkbp:alsoKnownAs	bad cholesterol
gptkbp:associatedWith	atherosclerosis
gptkbp:component	blood plasma
gptkbp:contains	gptkb:apolipoprotein_B-100 phospholipids triglycerides cholesteryl esters free cholesterol
gptkbp:decreasedIn	gptkb:PCSK9_inhibitors gptkb:ezetimibe niacin exercise weight loss dietary fiber statins omega-3 fatty acids plant sterols bile acid sequestrants
gptkbp:elevatedLevel	gptkb:familial_hypercholesterolemia
gptkbp:function	transports cholesterol
https://www.w3.org/2000/01/rdf-schema#label	Low-density lipoprotein (LDL)
gptkbp:improves	saturated fat trans fat
gptkbp:measures	blood test
gptkbp:oxidizedForm	oxidized LDL (oxLDL)
gptkbp:oxidizedFormAssociatedWith	inflammation endothelial dysfunction
gptkbp:predecessor	very-low-density lipoprotein (VLDL)
gptkbp:producedBy	liver intestine
gptkbp:range	less than 100 mg/dL (desirable)
gptkbp:recipient	gptkb:LDL_receptor
gptkbp:relatedTo	gptkb:high-density_lipoprotein_(HDL) gptkb:intermediate-density_lipoprotein_(IDL) chylomicron very-low-density lipoprotein (VLDL)
gptkbp:riskFactor	myocardial infarction stroke coronary artery disease peripheral artery disease atherosclerotic plaque
gptkbp:role	cholesterol homeostasis
gptkbp:significance	risk factor for cardiovascular disease
gptkbp:studiedIn	gptkb:Framingham_Heart_Study
gptkbp:target	gptkb:PCSK9_inhibitors gptkb:ezetimibe statins
gptkbp:type	cholesterol
gptkbp:bfsParent	gptkb:Cholesterol
gptkbp:bfsLayer	6