Loss of Heterozygosity

GPTKB entity

Statements (19)
Predicate Object
gptkbp:instanceOf Genetic phenomenon
gptkbp:abbreviation gptkb:LOH
gptkbp:affects tumor suppressor genes
gptkbp:associatedWith genomic instability
gptkbp:cause deletion
mitotic recombination
gene conversion
chromosomal nondisjunction
unmasking of recessive mutations
gptkbp:detects SNP array
microsatellite analysis
gptkbp:firstDescribed gptkb:retinoblastoma
https://www.w3.org/2000/01/rdf-schema#label Loss of Heterozygosity
gptkbp:involves loss of one parental allele
gptkbp:occurredIn gptkb:cancer
gptkbp:relatedTo hereditary cancer syndromes
gptkbp:studiedIn molecular genetics
gptkbp:bfsParent gptkb:LOH
gptkbp:bfsLayer 8