Library of Integrated Network-based Cellular Signatures (LINCS)

URI: https://gptkb.org/entity/Library_of_Integrated_Network-based_Cellular_Signatures_(LINCS)

GPTKB entity

Statements (52)

Predicate	Object
gptkbp:instanceOf	biomedical research program
gptkbp:abbreviation	gptkb:LINCS
gptkbp:application	precision medicine drug discovery disease mechanism elucidation biomarker identification
gptkbp:collaboratesWith	gptkb:Broad_Institute gptkb:Columbia_University gptkb:Harvard_Medical_School gptkb:University_of_Miami gptkb:Icahn_School_of_Medicine_at_Mount_Sinai
gptkbp:country	gptkb:United_States
gptkbp:dataSource	gptkb:REST_API gptkb:LINCS_Data_Portal open access bulk download
gptkbp:focus	systems biology cellular response to perturbations gene expression profiling high-throughput data
gptkbp:format	gptkb:JSON gptkb:GCT CSV Level 1-5 data
gptkbp:fundedBy	gptkb:National_Institutes_of_Health gptkb:NIH_Common_Fund
gptkbp:goal	catalog cellular responses to a variety of perturbing agents enable discovery of relationships between diseases, genes, and therapeutics
gptkbp:hasComponent	gptkb:LINCS_Data_Portal gptkb:LINCS_Cloud gptkb:LINCS_Data_Coordination_and_Integration_Center gptkb:LINCS_Data_Working_Group gptkb:LINCS_Data_and_Signature_Generation_Centers
https://www.w3.org/2000/01/rdf-schema#label	Library of Integrated Network-based Cellular Signatures (LINCS)
gptkbp:notableProject	gptkb:L1000_assay gptkb:Cell_Painting_assay
gptkbp:notablePublication	gptkb:Keenan_et_al.,_Nucleic_Acids_Research,_2018 Subramanian et al., Cell, 2017
gptkbp:principalInvestigator	gptkb:Todd_Golub gptkb:Aravind_Subramanian gptkb:Avi_Ma’ayan
gptkbp:relatedTo	gptkb:Connectivity_Map gptkb:NIH_Common_Fund_Data_Ecosystem
gptkbp:startYear	2010
gptkbp:type	proteomics cellular imaging transcriptomics small molecule perturbations
gptkbp:website	https://lincsproject.org/
gptkbp:bfsParent	gptkb:NIH_Common_Fund gptkb:LINCS_L1000_dataset
gptkbp:bfsLayer	6