|
gptkbp:instanceOf
|
neurodegenerative disease
|
|
gptkbp:affects
|
brain
elderly adults
|
|
gptkbp:alsoKnownAs
|
gptkb:LBD
|
|
gptkbp:associatedWith
|
gptkb:GBA_gene_mutation
gptkb:SNCA_gene_mutation
|
|
gptkbp:characterizedBy
|
abnormal aggregates of alpha-synuclein protein
|
|
gptkbp:diagnosedBy
|
brain imaging
clinical assessment
neurological examination
|
|
gptkbp:firstDescribed
|
1912
|
|
gptkbp:hasPathologicalFeature
|
gptkb:Lewy_neurites
Lewy bodies
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Lewy body disease
|
|
gptkbp:ICD-10_code
|
G31.8
|
|
gptkbp:MeSH_ID
|
D020961
|
|
gptkbp:namedAfter
|
gptkb:Friedrich_Heinrich_Lewy
|
|
gptkbp:prevalence
|
second most common cause of degenerative dementia after Alzheimer's disease
|
|
gptkbp:prognosis
|
progressive
incurable
|
|
gptkbp:relatedTo
|
gptkb:Alzheimer's_disease
gptkb:Parkinson's_disease
|
|
gptkbp:riskFactor
|
age
family history
male sex
|
|
gptkbp:subspecies
|
gptkb:Parkinson's_disease_dementia
gptkb:dementia_with_Lewy_bodies
|
|
gptkbp:symptom
|
gptkb:dementia
gptkb:REM_sleep_behavior_disorder
fluctuating cognition
parkinsonism
visual hallucinations
|
|
gptkbp:treatment
|
occupational therapy
physical therapy
antipsychotic drugs (with caution)
cholinesterase inhibitors
|
|
gptkbp:bfsParent
|
gptkb:Otis_Chandler
gptkb:dementia
|
|
gptkbp:bfsLayer
|
5
|