|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
lactoferrin
|
|
gptkbp:antibacterialActivityAgainst
|
gptkb:Staphylococcus_aureus
gptkb:Bacteria
|
|
gptkbp:antifungalActivityAgainst
|
gptkb:Candida_albicans
|
|
gptkbp:antiviralActivityAgainst
|
gptkb:herpes_simplex_virus
gptkb:HIV
|
|
gptkbp:binds
|
iron
glycosaminoglycans
lipopolysaccharide
|
|
gptkbp:concentrationInCowMilk
|
0.1-0.3 g/L
|
|
gptkbp:concentrationInHumanMilk
|
1-3 g/L
|
|
gptkbp:contributedTo
|
innate immunity
|
|
gptkbp:degradedBy
|
proteases
|
|
gptkbp:discoveredIn
|
1960
|
|
gptkbp:encodedBy
|
LTF gene
|
|
gptkbp:Entrez_Gene_ID
|
4057 (human)
|
|
gptkbp:firstIsolatedFrom
|
bovine milk
|
|
gptkbp:foundIn
|
gptkb:milk
tears
saliva
mucus
neutrophil granules
|
|
gptkbp:function
|
immune modulation
antimicrobial activity
iron-binding
|
|
gptkbp:glycosylation
|
yes
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Lactotransferrin
|
|
gptkbp:inhibitedBy
|
fungal growth
viral entry
bacterial growth
|
|
gptkbp:locatedOnChromosome
|
3q21-q23 (human)
|
|
gptkbp:molecularWeight
|
~80 kDa
|
|
gptkbp:OMIM
|
150700
|
|
gptkbp:PDB
|
1B0L
|
|
gptkbp:pI
|
~8.7
|
|
gptkbp:presentIn
|
gptkb:cow_milk
human milk
other mammalian milks
|
|
gptkbp:promotion
|
cell proliferation
differentiation
|
|
gptkbp:regulates
|
inflammatory response
|
|
gptkbp:stable
|
iron binding
|
|
gptkbp:structure
|
two-lobed glycoprotein
|
|
gptkbp:UniProtID
|
P02788 (human)
|
|
gptkbp:usedAs
|
dietary supplement
|
|
gptkbp:usedIn
|
cosmetics
infant formula
nutraceuticals
|
|
gptkbp:bfsParent
|
gptkb:Transferrin
|
|
gptkbp:bfsLayer
|
7
|