Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:catalyzes |
conversion of lactate to pyruvate
|
| gptkbp:cofactor |
NAD+
|
| gptkbp:EC_number |
1.1.1.27
|
| gptkbp:foundIn |
gptkb:skeletal_muscle
gptkb:kidney brain heart red blood cells |
| gptkbp:fullName |
Lactate dehydrogenase 1
|
| gptkbp:gene |
gptkb:LDHB
|
| https://www.w3.org/2000/01/rdf-schema#label |
LDH1
|
| gptkbp:isoenzymeOf |
gptkb:lactate_dehydrogenase
|
| gptkbp:molecularWeight |
~140 kDa (tetramer)
|
| gptkbp:significance |
elevated in myocardial infarction
used in diagnosis of heart attack |
| gptkbp:structure |
tetrameric protein
|
| gptkbp:subunit |
gptkb:H_(heart)_subunit
tetramer of H (heart) subunits |
| gptkbp:type |
lactate + NAD+ ⇌ pyruvate + NADH + H+
|
| gptkbp:bfsParent |
gptkb:LDHE
|
| gptkbp:bfsLayer |
7
|