Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:associatedWith |
familial LCAT deficiency
fish eye disease |
| gptkbp:cofactor |
apoA-I
apoA-IV |
| gptkbp:discoveredBy |
1962
|
| gptkbp:EC_number |
2.3.1.43
|
| gptkbp:enzymeClassification |
transferase
|
| gptkbp:expressedIn |
gptkb:testis
brain liver |
| gptkbp:fullName |
lecithin–cholesterol acyltransferase
|
| gptkbp:function |
catalyzes the esterification of cholesterol
|
| gptkbp:gene |
gptkb:LCAT
|
| gptkbp:HGNC_ID |
HGNC:6526
|
| https://www.w3.org/2000/01/rdf-schema#label |
LCAT
|
| gptkbp:involvedIn |
reverse cholesterol transport
|
| gptkbp:locatedOnChromosome |
16q22.1
|
| gptkbp:location |
blood plasma
|
| gptkbp:molecularWeight |
63 kDa
|
| gptkbp:mutationAssociatedWith |
kidney disease
corneal opacities low HDL cholesterol |
| gptkbp:OMIM |
606967
|
| gptkbp:PDB |
4XAK
|
| gptkbp:product |
cholesteryl ester
lysolecithin |
| gptkbp:regulates |
HDL metabolism
|
| gptkbp:substrate |
cholesterol
lecithin |
| gptkbp:UniProtID |
P04180
|
| gptkbp:bfsParent |
gptkb:APOA1
|
| gptkbp:bfsLayer |
7
|