Statements (13)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
point mutation
|
| gptkbp:affects |
gptkb:epidermal_growth_factor_receptor
|
| gptkbp:aminoAcidChange |
leucine to arginine
|
| gptkbp:associatedWith |
gptkb:non-small_cell_lung_cancer
|
| gptkbp:detects |
DNA sequencing
|
| gptkbp:firstDescribed |
2004
|
| gptkbp:foundInGene |
gptkb:EGFR
|
| https://www.w3.org/2000/01/rdf-schema#label |
L858R mutation
|
| gptkbp:position |
858
|
| gptkbp:sensitivity |
gptkb:EGFR_tyrosine_kinase_inhibitors
|
| gptkbp:significance |
predictive biomarker
|
| gptkbp:bfsParent |
gptkb:EGFR_mutation-positive_NSCLC
|
| gptkbp:bfsLayer |
7
|