Statements (19)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
scientific theory
|
| gptkbp:alsoKnownAs |
gptkb:two-hit_hypothesis
|
| gptkbp:citation |
numerous scientific articles
|
| gptkbp:describes |
mechanism of cancer development
|
| gptkbp:explains |
difference between hereditary and non-hereditary cancer forms
|
| gptkbp:field |
genetics
oncology |
| gptkbp:focusesOn |
tumor suppressor genes
|
| https://www.w3.org/2000/01/rdf-schema#label |
Knudson hypothesis
|
| gptkbp:influenced |
cancer genetics
|
| gptkbp:originallyStudied |
gptkb:retinoblastoma
|
| gptkbp:proposedBy |
gptkb:Alfred_G._Knudson
|
| gptkbp:publishedIn |
gptkb:Proceedings_of_the_National_Academy_of_Sciences
|
| gptkbp:relatedTo |
hereditary cancer
sporadic cancer |
| gptkbp:state |
two mutational events are required for cancer to develop
|
| gptkbp:yearProposed |
1971
|
| gptkbp:bfsParent |
gptkb:Alfred_G._Knudson
|
| gptkbp:bfsLayer |
7
|