|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
Kinesin heavy chain isoform 5B
Kinesin-1 heavy chain
|
|
gptkbp:associatedWith
|
gptkb:lung_adenocarcinoma
KIF5B-RET fusion in cancer
|
|
gptkbp:biologicalProcess
|
gptkb:axonal_transport
mitosis
vesicle-mediated transport
ATPase activity
microtubule binding
|
|
gptkbp:discoveredBy
|
1990s
|
|
gptkbp:encodes
|
Kinesin family member 5B
|
|
gptkbp:Entrez_Gene_ID
|
3799
ENSG00000142945
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
gptkb:kidney
brain
liver
|
|
gptkbp:function
|
intracellular transport
organelle transport
microtubule-based motor protein
|
|
gptkbp:gene
|
gptkb:KIF5B
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GO_term
|
GO:0003777 (microtubule motor activity)
GO:0007018 (microtubule-based movement)
|
|
gptkbp:HGNC_ID
|
HGNC:6319
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
KIF5B
|
|
gptkbp:interactsWith
|
gptkb:APP
microtubules
KLC1
KLC2
SNAPIN
|
|
gptkbp:length
|
963
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_10p11.22
|
|
gptkbp:molecularWeight
|
110 kDa
|
|
gptkbp:mutationAssociatedWith
|
associated with neurodevelopmental disorders
|
|
gptkbp:OMIM
|
602809
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Kif5b
|
|
gptkbp:PDB
|
3KIN
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
|
gptkbp:proteinFamily
|
kinesin family
|
|
gptkbp:RefSeq
|
NM_004521
|
|
gptkbp:subcellularLocation
|
gptkb:cytoplasm
microtubule
|
|
gptkbp:UniProtID
|
P33176
|
|
gptkbp:bfsParent
|
gptkb:RET_fusion-positive_thyroid_cancer
gptkb:KIF5
|
|
gptkbp:bfsLayer
|
7
|