Statements (12)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
|
| gptkbp:CASNumber |
1801747-30-5
|
| gptkbp:clinicalTrialPhase |
Phase 1
|
| gptkbp:developedBy |
gptkb:Japan_Tobacco_Inc.
|
| gptkbp:function |
inhibitor of IDH1 mutant enzyme
|
| gptkbp:hasMolecularFormula |
C20H18ClFN4O2
|
| https://www.w3.org/2000/01/rdf-schema#label |
JTP-4819
|
| gptkbp:intendedUse |
anticancer agent
|
| gptkbp:mechanismOfAction |
inhibits mutant IDH1 to reduce 2-hydroxyglutarate production
|
| gptkbp:target |
isocitrate dehydrogenase 1 (IDH1) mutant
|
| gptkbp:bfsParent |
gptkb:prolyl_endopeptidase
|
| gptkbp:bfsLayer |
7
|