Statements (67)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:Cell
|
| gptkbp:associated_with |
Th1 cell differentiation
|
| gptkbp:enhances |
T cell activation
IFN-gamma production B cell responses |
| gptkbp:function |
promotes inflammation
|
| gptkbp:has_receptor |
IL-18 R
|
| gptkbp:has_role |
autoimmune diseases
|
| https://www.w3.org/2000/01/rdf-schema#label |
Il-18
|
| gptkbp:initiated_by |
apoptosis
NF-k B pathway |
| gptkbp:interacts_with |
IL-12
|
| gptkbp:involved_in |
immune response
|
| gptkbp:is_associated_with |
gptkb:disease
gptkb:asthma gptkb:chronic_fatigue_syndrome gptkb:rheumatoid_arthritis gptkb:systemic_sclerosis chronic pain mental health disorders tuberculosis |
| gptkbp:is_expressed_in |
various tissues
|
| gptkbp:is_involved_in |
gptkb:disease
gptkb:sickle_cell_disease gptkb:endometriosis gptkb:multiple_sclerosis hepatitis allergic reactions neuroinflammation fibrosis cardiovascular diseases sepsis psoriasis cancer progression aging process tissue repair viral infections chronic obstructive pulmonary disease cancer immunotherapy HIV infection pain modulation host defense mechanisms auto-inflammatory syndromes |
| gptkbp:is_linked_to |
gptkb:diabetes
gptkb:cystic_fibrosis gptkb:Canis_lupus gptkb:neurodegenerative_diseases metabolic syndrome obesity sleep disorders chronic kidney disease atherosclerosis pregnancy complications chronic inflammatory diseases |
| gptkbp:is_part_of |
innate immunity
|
| gptkbp:is_regulated_by |
IL-10
|
| gptkbp:is_studied_in |
clinical trials
|
| gptkbp:is_targeted_at |
therapeutic agents
|
| gptkbp:measures |
serum levels
|
| gptkbp:participated_in |
cytokine production
|
| gptkbp:produced |
gptkb:disease
|
| gptkbp:produced_by |
macrophages
dendritic cells response to pathogens |
| gptkbp:security |
NK cells
|
| gptkbp:bfsParent |
gptkb:Soviet_Air_Forces
|
| gptkbp:bfsLayer |
4
|