Statements (64)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
cytokine
|
| gptkbp:associatedWith |
autoimmune diseases
|
| gptkbp:canBe |
IL-6 production
serum levels |
| gptkbp:canEstablish |
B cell activation
NK cell activity T helper cell responses |
| gptkbp:canLeadTo |
cytokine production
|
| gptkbp:function |
promotes inflammation
|
| gptkbp:hasInventor |
IL-18 receptor
|
| gptkbp:hasProductLine |
inflammatory responses
response to pathogens |
| https://www.w3.org/2000/01/rdf-schema#label |
Il-18
|
| gptkbp:interactsWith |
IL-12
|
| gptkbp:involvedIn |
immune response
chronic inflammatory diseases |
| gptkbp:isActiveIn |
apoptosis
|
| gptkbp:isAssociatedWith |
Crohn's disease
obesity cardiovascular diseases chronic kidney disease rheumatoid arthritis psoriatic arthritis chronic obstructive pulmonary disease (COPD) |
| gptkbp:isAttendedBy |
dendritic cells
|
| gptkbp:isEngagedIn |
anti-inflammatory cytokines
|
| gptkbp:isInvolvedIn |
neurodegenerative diseases
allergic reactions asthma chronic pain metabolic syndrome neuroinflammation fibrosis cystic fibrosis psoriasis atherosclerosis viral infections tuberculosis gout lupus erythematosus scleroderma Th2 response chronic hepatitis chronic urticaria graft-versus-host disease (GVHD) |
| gptkbp:isLinkedTo |
multiple sclerosis
sepsis chronic fatigue syndrome type 1 diabetes endometriosis HIV infection inflammatory bowel disease (IBD) systemic sclerosis |
| gptkbp:isLocatedIn |
various tissues
|
| gptkbp:isPartOf |
innate immune system
|
| gptkbp:isRegulatedBy |
NF-kB
|
| gptkbp:isStudiedIn |
clinical trials
|
| gptkbp:isTrainedIn |
therapeutic antibodies
|
| gptkbp:isVisitedBy |
macrophages
|
| gptkbp:participatesIn |
cancer progression
|
| gptkbp:producedBy |
macrophages
|
| gptkbp:regulates |
Th1 cell differentiation
|
| gptkbp:sparked |
T cells
|
| gptkbp:updates |
IFN-gamma production
|