Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
immunoglobulin G subclass
|
| gptkbp:activatedBy |
complement system (weakly)
|
| gptkbp:binds |
FcγRIIA receptor
FcγRIIB receptor |
| gptkbp:composedOf |
about 20% of total IgG in human serum
|
| gptkbp:deficiencyAssociatedWith |
recurrent bacterial infections
|
| gptkbp:doesNotBind |
FcγRI receptor
FcγRIII receptor |
| gptkbp:encodedBy |
IGHG2 gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
immune response to polysaccharide antigens
|
| gptkbp:halfLife |
21 days
|
| gptkbp:hasDisulfideBonds |
unique hinge region disulfide bonds
|
| gptkbp:hasHeavyChain |
gamma-2 chain
|
| gptkbp:hasSerumConcentration |
2-4 mg/mL
|
| https://www.w3.org/2000/01/rdf-schema#label |
IgG2 subclass (human)
|
| gptkbp:importantFor |
defense against encapsulated bacteria
|
| gptkbp:isotypeOf |
gptkb:immunoglobulin_G_(IgG)
|
| gptkbp:isotypeSwitching |
occurs in response to T-independent antigens
|
| gptkbp:molecularWeight |
146 kDa
|
| gptkbp:structure |
four constant domains in heavy chain
|
| gptkbp:bfsParent |
gptkb:Protein_A
|
| gptkbp:bfsLayer |
7
|