Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
immunoglobulin G subclass
|
| gptkbp:abundanceInSerum |
~60-70% of total IgG
|
| gptkbp:allotype |
G1m
|
| gptkbp:binds |
gptkb:FcγRIII_(CD16)
FcγRI (CD64) FcγRII (CD32) |
| gptkbp:encodedBy |
IGHG1 gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
antibody-dependent cellular cytotoxicity
opsonization complement activation neutralization of pathogens |
| gptkbp:halfLife |
~21 days
|
| gptkbp:hasHeavyChain |
gamma-1 heavy chain
|
| https://www.w3.org/2000/01/rdf-schema#label |
IgG1 subclass (human)
|
| gptkbp:isotypeOf |
gptkb:IgG
|
| gptkbp:medicalUse |
therapeutic monoclonal antibodies
|
| gptkbp:molecularWeight |
146 kDa
|
| gptkbp:presentIn |
blood
extracellular fluid |
| gptkbp:structure |
two heavy chains, two light chains
|
| gptkbp:bfsParent |
gptkb:Protein_A
|
| gptkbp:bfsLayer |
7
|