Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
immune system
|
| gptkbp:encodes |
Integrin beta-7 protein
|
| gptkbp:Entrez_Gene_ID |
3695
|
| gptkbp:expressedIn |
gptkb:leukocytes
gptkb:gut-associated_lymphoid_tissue |
| gptkbp:formsComplexWith |
Integrin alpha-E
Integrin alpha-4 |
| gptkbp:function |
cell surface receptor activity
mediates lymphocyte migration to gut |
| gptkbp:HGNC_ID |
6150
|
| https://www.w3.org/2000/01/rdf-schema#label |
ITGB7 gene
|
| gptkbp:involvedIn |
cell adhesion
lymphocyte homing |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_12
12q13.13 |
| gptkbp:mutationAssociatedWith |
ulcerative colitis
inflammatory bowel disease |
| gptkbp:OMIM |
147606
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
gptkb:mouse
right |
| gptkbp:proteinFamily |
integrin beta chain family
|
| gptkbp:target |
therapeutic antibodies
|
| gptkbp:UniProtID |
P26010
|
| gptkbp:bfsParent |
gptkb:alpha-4_beta-7_integrin
|
| gptkbp:bfsLayer |
7
|