|
gptkbp:instanceOf
|
gptkb:antibiotic
|
|
gptkbp:approvalYear
|
2017
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
gptkb:J01DH56
|
|
gptkbp:brand
|
gptkb:Vabomere
|
|
gptkbp:contains
|
gptkb:vaborbactam
gptkb:imipenem
|
|
gptkbp:contraindication
|
hypersensitivity to carbapenems
severe allergic reactions to beta-lactams
|
|
gptkbp:discoveredBy
|
gptkb:Rempex_Pharmaceuticals
|
|
gptkbp:fullName
|
gptkb:Imipenem/Vaborbactam
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
IMPV
|
|
gptkbp:indication
|
carbapenem-resistant Enterobacteriaceae infections
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:marketedAs
|
gptkb:Melinta_Therapeutics
|
|
gptkbp:mechanismOfAction
|
inhibits bacterial cell wall synthesis
inhibits beta-lactamase enzymes
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:routeOfAdministration
|
intravenous
|
|
gptkbp:sideEffect
|
nausea
diarrhea
headache
infusion site reactions
|
|
gptkbp:usedFor
|
treatment of ventilator-associated bacterial pneumonia
treatment of complicated urinary tract infections
treatment of hospital-acquired bacterial pneumonia
|
|
gptkbp:bfsParent
|
gptkb:Imperva
|
|
gptkbp:bfsLayer
|
6
|