IMPDH family

GPTKB entity

Statements (19)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:associatedWith retinitis pigmentosa (IMPDH1 mutations)
gptkbp:cofactor NAD+
gptkbp:contains gptkb:IMPDH1
IMPDH2
gptkbp:EC_number 1.1.1.205
gptkbp:enzymeClassification oxidoreductase
gptkbp:foundIn gptkb:Bacteria
archaea
eukaryotes
gptkbp:fullName Inosine-5'-monophosphate dehydrogenase family
gptkbp:function catalyzes conversion of IMP to XMP
https://www.w3.org/2000/01/rdf-schema#label IMPDH family
gptkbp:inhibitedBy gptkb:mycophenolic_acid
ribavirin
gptkbp:memberOf purine metabolism pathway
gptkbp:structure TIM barrel fold
gptkbp:bfsParent gptkb:IMPDH1_gene
gptkbp:bfsLayer 7