Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:affects |
cancer progression
metabolic diseases tissue development growth hormone action |
| gptkbp:binds |
gptkb:insulin-like_growth_factors
|
| gptkbp:canBe |
proteolytically cleaved
|
| gptkbp:encodedBy |
IGFBP genes
|
| gptkbp:foundIn |
blood plasma
extracellular space |
| gptkbp:heldBy |
glycoproteins
secreted proteins high affinity for IGFs |
| https://www.w3.org/2000/01/rdf-schema#label |
IGF-binding proteins
|
| gptkbp:include |
gptkb:IGFBP-1
IGFBP-2 IGFBP-3 IGFBP-4 IGFBP-5 IGFBP-6 |
| gptkbp:influenced |
IGF receptor interaction
|
| gptkbp:involves |
endocrine regulation
autocrine regulation paracrine regulation |
| gptkbp:modulatedBy |
apoptosis
cell differentiation metabolism cell growth |
| gptkbp:regulates |
IGF bioavailability
IGF activity |
| gptkbp:bfsParent |
gptkb:Insulin-like_Growth_Factor
|
| gptkbp:bfsLayer |
7
|